HNRP associated studies primarily focus on understanding the effect of HIV and co-factors on the central nervous system (CNS). Major themes include research into cognitive impairment, neurologic disorders, and antiretroviral issues (for example, understanding and optimizing CNS treatment, drug resistance, etc.), especially in the context of co-factors such as methamphetamine abuse and aging.
(619) 543-5000
Phone:
Current Clinical Trials
Cannabis Effects on Antiretroviral Therapy, Pharmacokinetics, and Neurotoxicity
Cannabis Effects on Antiretroviral Therapy, Pharmacokinetics, and Neurotoxicity
Status: Enrolling
Summary:
Are you HIV positive and on stable Antiretroviral Therapy (ART)? We want to
learn if cannabis has an effect on your ART regimen. If interested, give us a call and find
out if you are eligible. The #1 requirement is that you’re on HIV meds. Other requirements
will be reviewed over the phone. Hope to hear from you soon!*
In order to participate you must be*:
Currently on a steady HIV treatment
Cannabis and non-cannabis users
Willing to do some concentration tests
For further details regarding this study, or other studies, please call (619) 543-5000 and ask to speak with a recruiter.
*Not all individuals are eligible to participate.
All information collected is kept strictly confidential.
Sponsor:
none
Measurement of ART Drug Concentrations in Brain by 19f-MRS as an Indicator of Neurotoxicity
Measurement of ART Drug Concentrations in Brain by 19f-MRS as an Indicator of Neurotoxicity
Status: Enrolling
Summary:
Participate in a one-time research visit looking at the effects of your current HIV medication
and your brain.
Study visit consists of:
A brief medical interview
A blood draw
An MRI
Visit lasts about 4 hours.
Compensation of $120
Transportation provided (within San Diego County)
You may qualify if you are taking any of the following HIV medications*:
Pifeltro (Doravirine)
Emtriva (Emtricitabine)
Tivicay, Juluca (Dolutegravir)
For further details regarding this study, or other studies, please call (619) 543-5000 and ask to speak with a recruiter.
Sponsor:
none
Cannabidiol for Sedative/Hypnotic-sparing Management of Insomnia in Adults
Cannabidiol for Sedative/Hypnotic-sparing Management of Insomnia in Adults
Status: Enrolling
Summary:
A randomized, double-blind placebo-controlled phase II study to examine the noninferiority and efficacious dose range of CBD in managing symptoms of insomnia compared to sedative/hypnotic medication. We will measure sleep outcomes objectively using wrist-worn actigraphy as well as by self-report via real-time ecological momentary assessment and traditional questionnaires. We will also compare objective next-morning neuropsychological performance.
Who can participate*:
Adults 18 and older
who have trouble falling asleep or staying asleep
who are not taking medications for sleep problems, or are willing to stop taking them.
You can receive up to $225 for participating in this study
For further details regarding this study, or other studies, please call (619) 543-5000 and ask to speak with a recruiter.
*Not all individuals are eligible to participate.
All information collected is kept strictly confidential.
Sponsor:
none
Nicotine and HIV Study
Nicotine and HIV Study
Effects of nicotine on the brain
1 visit – baseline only – (8 hours)
Some candidates may qualify: MRI / PET visits separately
HIV+/-
Current Smokers
Initial screen (1 hour)
1 visit - Compensation up to $90
Possible MRI and or PET scan addtional compensation up to $177.40
For futher details regarding this study, or other studies please call (619) 543-5000 and ask to speak with a recruiter and view the pdf below.
Sponsor:
none
Health in Older Latinos Study
Health in Older Latinos Study
Ethnic and racial differences in the cognitive effects of HIV
3visits -3years
Latino HIV+/-
Spanish or English
Initial screen (1 hour)
Compensation up to $305
For futher details regarding this study, or other studies please call (619) 543-5000 and ask to speak with a recruiter and view the pdf below.
Sponsor:
none
Potential Benefits of Egrifta on the Brain
Potential Benefits of Egrifta on the Brain
Status: Enrolling
Summary:
The HNRP-CMCR at UCSD is conducting a study examining the potential benefits of Egrifta® on the brain.
What is Egrifta*:
Injectable prescription medication
Contains growth hormone-releasing factor
Reduces excess abdominal fat in HIV-infected individuals with lipodystrophy
In order to participate you must be*:
HIV positive with abdominal fat
Ages 40 and up
Currently on stable antiretroviral therapy
Wiling to do MRIs
Other information
Lab results (at no cost to you)
Monetary compensation
Free 6 months supply of Egrifta®
For further details regarding this study, or other studies, please call (619) 543-5000 and ask to speak with a recruiter.
*Not all individuals are eligible to participate.
All information collected is kept strictly confidential.
Sponsor:
none
Virtual Reality Assessment of How HIV Affects Cognitive and Balance Problems
Virtual Reality Assessment Study
VR assessment for Cognitive and Balance
2.5-year study
HIV+ 60+y/o
Initial screen (1 - 1 1⁄2 hours)
8 visits over 2 years
5 HNRP visits – (full & partial visits)
3 SDSU visits for hearing tests
Compensation up to $390
For futher details regarding this study, or other studies please call (619) 543-5000 and ask to speak with a recruiter and view the pdf below.
Sponsor:
none